Luminary of Modern Human Genetics

In this episode of More Intelligent Tomorrow podcast, Dr. Lee Hood shares his vision on how human and artificial intelligence collaborate to unravel the human genome and impact the future of wellness and disease through the power of AI.

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Guests

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Dr. Lee Hood

Chief Science Officer, Institute for Systems Biology

Dr. Leroy (Lee) Hood is Chief Science Officer of Providence St. Joseph Health and co-founder of the Institute for Systems Biology. He is well-known in the industry for developing the first DNA sequencer, which led to the Human Genome Project. He introduced the term “systems biology,” co-founded 17 biotech companies, including Amgen with a $131 billion market cap.


“Maybe we could get you a meeting with Bill Gates and he could help you.” And he said, “What I’m going to do is invite you to give three lectures here, and give us your view of what the future of biology in medicine is.” And Bill went to all of those lectures. And then after I’d finished, we had dinner and sat and talked for two-and-a-half or three hours about all these possibilities. And then Bill made an offer to help support. The idea was for me to come up and to develop a department of molecular biotechnology, which was really cross-disciplinary in nature.
Lee Hood 1
Lee Hood 1

Lee Hood 2
Lee Hood 2
Linus Pauling gave a lecture and he was a master at building molecules with complicated tinker toy configurations, and all of a sudden the molecule exploded in his face. That just brought a roar of laughter and Pauling just turned to the audience and said, ” Gentlemen, that was an unstable molecule.” And then he walked out to enormous applause.

We developed the key algorithms for the Human Genome Project. That is how to assess the quality of DNA sequence that was generated and how you assemble all the small fragments that were sequenced into their long 270 megabase chromosomal stretches, and so forth.
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Lee Hood 3

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